Acne Scar.
Conditions
Interventions
Intervention 1: The first group: three times every three weeks (days 1-21-42) on one side of the face MN alone and on the other side MN + HUCBS with a dose of 2% microneedling. Intervention 2: The sec
Sponsors
Research Vice President of Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: Patients with rolling acne scars with different severity (according to the Goodman grading system) Complete consent of the patient to participate in the plan Age 18 years and above and less than 50 years.
Exclusion criteria
Exclusion criteria: Being positive in terms of the following: active inflammatory acne, active herpes labialis, local infections in the treatment area, prone to keloids, malignancy, pregnancy, breastfeeding, taking drugs that can affect bleeding or clotting mechanisms, immunosuppression, use of local and systemic steroids, systemic diseases), high blood pressure, diabetes, heart, kidney and liver diseases) Using peels 4 weeks before treatment It should not be done in areas where botulinum injection has been done due to the possibility of microneedle toxin release Positive history of bleeding or platelet disorder, positive history of major surgery in the last 6 months, presence of any acute facial infection such as herpes, folliculitis. HIV patients, HBsAg or any chronic disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The improvement rate of the depth of acne scars and the amount of skin spots and pores. Timepoint: Biometric tests will be done on the first day before the treatment and one month after the treatment. Method of measurement: Visioface.;The thickness and density of the skin. Timepoint: Biometric tests will be done on the first day before the treatment and one month after the treatment. Method of measurement: Sonography.;Elasticity and plasticity of the skin. Timepoint: Biometric tests will be done on the first day before the treatment and one month after the treatment. Method of measurement: Cutometer. | — |
Secondary
| Measure | Time frame |
|---|---|
| Safety and Efficacy. Timepoint: Safety checks are done before and after each treatment. Method of measurement: Patient history and the examination and diagnosis of the attending physician. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactEhsan Taghiabadi
Tehran University of Medical Sciences
Outcome results
None listed