Skin Rejuvenation.
Conditions
Interventions
Intervention 1: Intervention group: 30 patients who will receive a patch injection on one side of their face along with the selected medium condition group. Intervention 2: Control group: The same 30
Sponsors
Skin and Stem Cell Research Center, University of Tehran
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
35 Years to 55 Years
Inclusion criteria
Inclusion criteria: Having the desired age range Full patient consent to participate in the project Not taking oral collagen Absence of active inflammatory acne on the skin Absence of local infections at the treatment site The skin at the treatment site is not prone to keloids. The patient does not have malignancy. The patient is not pregnant or breastfeeding. Not having blood clotting diseases or platelet disorders and not taking medications that affect bleeding and blood clotting mechanisms. No immune suppression Not using topical or systemic steroids Absence of systemic diseases such as high blood pressure, diabetes, cardiovascular disease, kidney disease, liver disease, etc. Not using exfoliants for four weeks prior to entering the plan. Avoid Botox injections on the face due to toxin release. No history of major surgery within the past six months. Absence of other acute infections on the face such as herpes (Herpes labialis) and folliculitis ??? ????? ?? ?????? ??? ???? ?????? ????? ?????? ? HIV
Exclusion criteria
Exclusion criteria: Lack of consent to continue treatment for any reason Failure to follow up with the patient Known sensitivity to components of the microneedle patch Severe allergic reaction to treatment Positive sensitivity test to conditioned medium
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The amount of skin wrinkles. Timepoint: Beginning and end of the intervention, two months after the intervention. Method of measurement: Visio Face device.;Skin elasticity and flexibility. Timepoint: Beginning and end of the intervention, two months after the intervention. Method of measurement: Cutometer device.;Skin moisture level. Timepoint: Beginning and end of the intervention, two months after the intervention. Method of measurement: Corneometer device.;The level of transparency, brightness and skin color. Timepoint: Beginning and end of the intervention, two months after the intervention. Method of measurement: Colorimeter device.;Skin thickness and density. Timepoint: Beginning and end of the intervention, two months after the intervention. Method of measurement: Sonography device. | — |
Secondary
| Measure | Time frame |
|---|---|
| The safety and efficacy of treatment. Timepoint: Beginning and end of the intervention, two months after the intervention. Method of measurement: Patient's medical report, form of treatment satisfaction and recovery status that is filled out by the patient. Results from the patient's biometric analysis. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactEhsan Taghiabadi
Tehran University of Medical Sciences
Outcome results
None listed