Acanthosis Nigricans project

A comparative study of efficacy and safety of Glycolic acid 70% peel with topical Tretinoin 0.05% in the treatment of Acanthosis Nigricans patients

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20221129056666N1

Enrollment

Registered

2023-01-24

Start date

2022-12-22

Completion date

Unknown

Last updated

2023-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acanthosis Nigricans. Acanthosis nigricans

Interventions

Intervention 1: Intervention group: Acanthosis Nigricans lesions of one side of the axilla/ groin is treated with Glycolic acid 70% for 4 sessions every 2 weeks. The result of treatment is compared wi

Eligibility

Sex/Gender

All

Age

12 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with Acanthosis Nigricans lesions of axilla or neck. Patients with the informed consent for participating in the study.

Exclusion criteria

Exclusion criteria: Pregnancy or Lactation Patients with underlying malignancy. Patients with contraindicatons for topical Tretinoin or Glycolic acid. History of treatment of the lesions in the past month.

Design outcomes

Primary

Measure	Time frame
Degree of resolution of Acanthosis Nigricans lesions. Timepoint: 8 weeks after initiation of therapy and 4 treatment sessions. Method of measurement: Comparison with pre treatment photographs.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactRana Samii

Tehran University of Medical Sciences

Raanasamiei@gmail.com+98 21 5563 0174

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026