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Investigating the effect of organosulfur compounds on children's lung infections

The effectiveness of oral compounds derived from Organosulfur as the treatment in pediatrics with pneumonia.

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20221129056657N2
Enrollment
70
Registered
2023-01-25
Start date
2023-01-20
Completion date
Unknown
Last updated
2023-03-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pneumonia. Bronchopneumonia, unspecified organism

Interventions

Intervention 1: Intervention group: Capsules derived from organosulfur (Nicovid capsules are ordered by Surin Salamat Sabz Tehran Company and produced by Esveh Pharmaceutical Company. Each capsule con

Sponsors

Hossein Niktale - the inventor of medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Years to 16 Years

Inclusion criteria

Inclusion criteria: Patient age 3 to 16 years The patient does not need a ventilator A patient with pneumonia and hospitalized in the special care, infectious and lung department

Exclusion criteria

Exclusion criteria: History of allergy to allicin-L-cysteine History of allergy to garlic and onion Patients with a history of hypotension or gastrointestinal bleeding Low blood pressure of the patient at the beginning of the study (below 120/80) Immune compromised patients - under chemotherapy, organ and bone marrow transplantation, and patients with autoimmune diseases The patient's inability to swallow oral medication that is not embedded in the NGtube or other delivery method.

Design outcomes

Primary

MeasureTime frame
Fever. Timepoint: The first day of the study before the start of the intervention and the seventh day of the study (the last day of the intervention). Method of measurement: Digital thermometer.;Blood oxygen (SpO2). Timepoint: The first day of the study before the start of the intervention and the seventh day of the study (the last day of the intervention). Method of measurement: Pulse Oximeter.;Erythrocyte Sedimentation Rate (ESR). Timepoint: The first day of the study before the start of the intervention and the seventh day of the study (the last day of the intervention). Method of measurement: Westergren method.

Secondary

MeasureTime frame
Blood pressure. Timepoint: At the beginning of the study (before the start of the intervention) and on the seventh day after the start of the intervention. Method of measurement: Mercury sphygmomanometer.;Heart beat. Timepoint: At the beginning of the study (before the start of the intervention) and on the seventh day after the start of the intervention. Method of measurement: Pulse oximeter.;Blood gases. Timepoint: At the beginning of the study (before the start of the intervention) and on the seventh day after the start of the intervention. Method of measurement: Blood gas measuring device.;C reactive protein. Timepoint: At the beginning of the study (before the start of the intervention) and on the seventh day after the start of the intervention. Method of measurement: Taking blood samples and laboratory kits.;Lactate dehydrogenase. Timepoint: At the beginning of the study (before the start of the intervention) and on the seventh day after the start of the intervention. Method of measurement: Electrophoresis method.;D-dimer. Timepoint: At the beginning of the study (before the start of the intervention) and on the seventh day after the start of the intervention. Method of measurement: Using Vidas laboratory kit.;Complete blood count(CBC). Timepoint: At the beginning of the study (before the start of the intervention) and on the seventh day after the start of the intervention. Method of measurement: Blood cell counting machine.;Ferritin. Timepoint: At the beginning of the study (before the start of the intervention) and on the seventh day after the start of the intervention. Method of measurement: Use of ELISA laboratory kit(Enzyme-linked immuno_sorbent assay).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactGholamreza Khademi

Mashhad University of Medical Sciences

khademigh@mums.ac.ir+98 51 3189 1780

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026