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Assessment of effect of L-Carnitine supplement on subclinical LV systolic dysfunction detected by speckletracking echocardiography in patients with ESRD under hemodiylisis

Assessment of effect of L-Carnitine supplement on subclinical LV systolic dysfunction detected by speckletracking echocardiography in patients with ESRD under hemodiylisis

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
IRCT
Registry ID
IRCT20221128056646N1
Enrollment
34
Registered
2022-12-18
Start date
2022-12-21
Completion date
Unknown
Last updated
2023-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with ESRD under hemodiylisis. speckle echo

Interventions

Intervention group: we do this study with L-Carnitine oral solution with dosage of 1000 mg right after each session of hemodialysis which prescribe for 3 months.the manufactor company is Bonyan Salama

Sponsors

Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Left ventricular ejection fraction more than or equal of 50 persent 3 times a weak routine and regular hemodialysis Agreement to take part in the study Hemodialysis patient with age more than 18 who start hemodialysis for more than 3 months If the pateint have been used L-Carnetine supplement before the study,should stop using it for at least 1 weak for entrance to our study

Exclusion criteria

Exclusion criteria: Pateint who used medicine which make drug intractions with the supplement Pateints who are pregnant or have Liver Failure , Thyroid dysfunction, Nephrotic syndrome,Cancers, Vasculitis or other inflamatory disease Disagreement to take part in the study

Design outcomes

Primary

MeasureTime frame
Ejection fraction is define with the ability of left venticle to pump blood in each haert beat and bring up with percent. Timepoint: Ejection fraction measure in the begining of study and the after 3months of recivining L-Carnitine supplements. Method of measurement: Speckle tracking echocardiography.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMina Keshtkar

Shiraz University of Medical Sciences

minakeshtkar_828@yahoo.com+98 71 3629 0110

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026