The effect of melatonin on endometrial thickness

Investigation of the effect of oral melatonin on the thickness of the endometrium of infertile women in the IUI cycle

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20221127056633N1

Enrollment

104

Registered

2023-04-03

Start date

2023-04-09

Completion date

Unknown

Last updated

2023-05-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility. Female infertility

Interventions

Intervention 1: Intervention group: In this group, 6 mg of melatonin which is prepared by Razak Pharmaceutical Company will be consumed from the 3rd day of menstruation (daily) until the end of the cy

Eligibility

Sex/Gender

Female

Age

18 Years to 42 Years

Inclusion criteria

Inclusion criteria: Full consent to participate in the study BMI less than 35 Women with low endometrial thickness No history of hospitalization and underlying diseases

Exclusion criteria

Exclusion criteria: Male infertility Simultaneous uterine anomalies Obstruction of uterine tubes Having a history of endometriosis AFC less than 10

Design outcomes

Primary

Measure	Time frame
Endometrial thickness. Timepoint: Measurement of endometrial thickness at the beginning of the study and 11 and 14 days after starting melatonin. Method of measurement: Ultrasound sonography.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShahin Taj Aramesh

Yasouj University of Medical Sciences

sh.aramesh@gmail.com+98 74 3333 7251

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026