Survey the effect of adding dexamethasone to ondansetrone or metoclopramide to increase the effect of these drugs in prevention of nausea and vomiting after caesarian section under spinal anesthesia

The adjuvant effect of dexamethasone to ondansetron or metoclopramide in prevention of nausea and vomiting after spinal anesthesia for elective caesarian section

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

IRCT

Registry ID

IRCT20221127056627N1

Enrollment

150

Registered

2022-12-04

Start date

2022-11-21

Completion date

Unknown

Last updated

2023-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

esarean section. Encounter for cesarean delivery without indication

Interventions

Intervention 1: Intervention group 1 or DO group: dexamethasone 8 mg (manufactured by Tehran-Shimi Company) IV plus ondansetron 4 mg (manufactured by Caspin Company ) is administered intravenously ten

Eligibility

Sex/Gender

Female

Age

18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Adult women with ASA grade I or II (American Society of Anesthesiology classification) Women between 18 and 35 years old Women having elective caesarean section under spinal anesthesia

Exclusion criteria

Exclusion criteria: ASA class of III or IV pregnancy induced Hypertension Patients who have received steroid medication positive history of prolonged QT interval patients who refuced to do spinal anesthesia for her

Design outcomes

Primary

Measure	Time frame
Nausea. Timepoint: 3 minutes and 15 minutes before the operation and 4 hours after the operation. Method of measurement: Score points based on Bellavia criteria.;Vomiting. Timepoint: 3 minutes and 15 minutes before the operation and 4 hours after the operation. Method of measurement: Score points based on Bellavia criteria.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMojtaba Sookhakian

Shiraz University of Medical Sciences

dr.sookhian.m@gmail.com0987136474270

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026