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The effect of tadalafil alone and tadalafil with tamsulosin in sexual dysfunction

Comparison the effect of tadalafil 20 mg alone and tadalafil 5 mg with tamsulosin on erectile dysfunction in diabetic patients

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20221127056624N2
Enrollment
154
Registered
2023-05-10
Start date
2021-07-16
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Erectile Dysfunction. Disorders of male genital organs in diseases classified elsewhere

Interventions

Intervention 1: Intervention group: Tadalafil 20 mg tablets(Farabi, Iran), one tablet daily for 4 weeks. Patients were evaluated before treatment, 4, 8, and 12 weeks after treatment by International P

Sponsors

Babol University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
50 Years to 70 Years

Inclusion criteria

Inclusion criteria: Known cases of diabetes with lower urinary tract symptoms and erectile dysfunction Age between 50-70 years With international prostate symptom score greater than 12 in who are treated with oral diabetes medications or insulin

Exclusion criteria

Exclusion criteria: Uncontrolled blood pressure Chronic kidney disease Liver failure Unstable coronary disease Psychiatric illness Contraindications to receiving tadalafil or tamsulosin Prostate malignancies bladder stones Retention history History of previous prostate surgery Urinary tract infection Neurogenic Bladder Treatment with finasteride in the last 6 months History of ductal stenosis History of bladder neck obstruction

Design outcomes

Primary

MeasureTime frame
Erectile Dysfunction. Timepoint: Before intervention, 4, 8 and 12 weeks after intervention. Method of measurement: The International Index of Erectile Function (IIEF).

Secondary

MeasureTime frame
Lower urinary tract symptoms. Timepoint: Before intervention, 4, 8 and 12 weeks after intervention. Method of measurement: The International Prostate Symptom Score (IPSS).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyyed Hossein Ghasemi

Babol University of Medical Sciences

ghosein591@gmail.com+98 11 3225 6285

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026