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The effect of preoperative antibiotic prophylaxis in ureteral stone crushing surgery

Effect of prophylactic antibiotics before intraureteral lithotripsy on infection and inflammatory factors

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20221127056624N1
Enrollment
80
Registered
2022-12-04
Start date
2022-12-15
Completion date
Unknown
Last updated
2023-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ureteral stone. Calculus of ureter

Interventions

Intervention 1: Intervention group: Intravenous antibiotic cefazolin with a dose of 1 gram (obtained from Aria Pharmaceutical Company) will be given intravenously half to one hour before the operation

Sponsors

Babol University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: All non-febrile hospitalized patients with negative preoperative cultures have ureteral stones

Exclusion criteria

Exclusion criteria: Age more than 65 years Heavy smoker (more than 25 cigarettes per day) Chronic steroid use Immunodeficiency Extracorporeal catheters Simultaneous infection of other parts of the body Long-term hospitalization

Design outcomes

Primary

MeasureTime frame
Assessing the patient's fever with a thermometer. Timepoint: 72 hours after surgery. Method of measurement: With a thermometer.;Evaluation of bacteriuria based on urinalysis and urine culture. Timepoint: 72 hours after surgery and one week and one month after surgery. Method of measurement: Evaluation of urinalysis and urine culture.

Secondary

MeasureTime frame
Examination of urine culture. Timepoint: 72 hours after surgery and one week and one month after surgery. Method of measurement: Urine culture test.;Urinalysis test. Timepoint: 72 hours after surgery and one week and one month after surgery. Method of measurement: Urinalysis test.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Omid Majidian

Babol University of Medical Sciences

aliaminids@gmail.com+98 11 3225 6285

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026