Infertility. Complications associated with artificial fertilization
Conditions
Interventions
Intervention 1: Intervention group: intrauterine infusion of human chorionic gonadotropin and embryo glue. In this group, 20 minutes before embryo transfer, 500 units of HCG (Pharmed Daru) and 15 micr
Sponsors
Mazandaran University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: Women who have a history of at least 3 failed transfer cycles or failed transfer of 4 good quality (grade A or B) embryos. Women who are in the frozen-thawed embryo transfer cycle and their preparation is done using estrogen and progesterone. Women who have at least one grade A or B embryo on the day of embryo transfer
Exclusion criteria
Exclusion criteria: Donated oocyte Donated embryo Surrogacy Presence of hydrosalpinx in hysterosalpingography or ultrasound History of uncontrolled endocrine diseases: diabetes, hypothyroidism and hyperthyroidism Male factor infertility (azoospermia) Difficult embryo transfer (needs manipulation of the cervix or under anesthesia) Uterine abnormalities Presence of severe endometriosis and endometrioma
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rate of Implantation. Timepoint: 5 weeks after intervention. Method of measurement: Ultrasound.;Rate of Abortion. Timepoint: 18 weeks after intervention. Method of measurement: Fetus excretion.;Rate of chemical pregnancy. Timepoint: 3-4 weeks after intervention. Method of measurement: Pregnancy test.;Rate of clinical pregnancy. Timepoint: 5 weeks after intervention. Method of measurement: Ultrasound.;Ongoing pregnancy. Timepoint: 38 weeks after intervention. Method of measurement: Delivery. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSepideh Peivandi
Mazandaran University of Medical Sciences
Outcome results
None listed