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Comparison of the effect of ketamine with fentanyl in control of acute pain after surgery

Comparison of the effect of perioperative intravenous ketamine with fentanyl in control of acute pain after inguinal hernia repair surgery

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20221126056613N5
Enrollment
60
Registered
2023-08-27
Start date
2023-04-21
Completion date
Unknown
Last updated
2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

inguinal hernia. Unilateral or unspecified inguinal hernia, without obstruction or gangrene

Interventions

Intervention 1: Intervention group: In ketamine group, Induction of anesthesia is done with 1 to 4 mg/kg of intravenous ketamine, and then in maintenance phase, intravenous perfusion of ketamine at a

Sponsors

Oroumia University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 60 Years

Inclusion criteria

Inclusion criteria: 30-60 aged adults with inguinal hernia Absence of contraindications for ketamine and opioids use patients with American Society of Anesthesiologist (ASA) physical status I,II

Exclusion criteria

Exclusion criteria: History of allergic reactions to the drug under study History of underlying diseases (diabetes, peptic ulcer, gastritis, coronary artery disease, renal failure) Any known psychiatric disorder Patients with incarcerated hernia patients with severe infection

Design outcomes

Primary

MeasureTime frame
Intensity of pain. Timepoint: At 60, 90 minutes and 24 hours after surgery. Method of measurement: Based on numeric rating scale (NRS).;The consumption of opioids for pain after surgery. Timepoint: Up to 24 hours after the surgery. Method of measurement: Based on milligrams.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Akbar Nasir

Oroumia University of Medical Sciences

Nasiriali7@gmail.com+98 44 3345 7286

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026