Skip to content

Comparison of the analgesic effect of oral Meloxicam and Diclofenac after knee arthroplasty

Comparison of the analgesic effect of oral Meloxicam and Diclofenac after knee arthroplasty

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20221126056613N4
Enrollment
128
Registered
2023-07-11
Start date
2023-05-21
Completion date
Unknown
Last updated
2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis of knee. Osteoarthritis of knee, unspecified

Interventions

Intervention 1: Intervention group:In the intervention group, the oral form of 15 mg meloxicam will be administered. Intervention 2: Control group: In the control group, the same method will be used,

Sponsors

Oroumia University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Diagnosis of knee osteoarthritis based on the scales of the American Society of Anesthesiology Candidate for knee joint replacement surgery American Society of Anesthesiology grade 1 and 2 physical status patients No history of corticosteroid or hyaluronic acid injections into the joint during the past three months No history of knee surgery or interventional treatment

Exclusion criteria

Exclusion criteria: Age less than 18 years pain reliever use in the past 7 days Blood and coagulation disorders Severe heart-liver and kidney failure Any absolute and relative contraindications to the use of drugs during the study Nervous disorders and the inability to accurately perceive the sensation of pain Pregnancy and breastfeeding Patients using the intravenous form of morphine

Design outcomes

Primary

MeasureTime frame
Intensity of pain. Timepoint: Pain intensity will be measured at 24, 48 and 72 hours after the operation. Method of measurement: The intensity of pain after the operation of the patients will be measured using a visual analog index and scoring method from 0 (no pain) to 10 (unbearable pain).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Akbar Nasir

Oroumia University of Medical Sciences

Nasiriali7@gmail.com+98 44 3345 7286

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026