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Assessing the effect of oral pregabalin in reducing pain after inguinal hernia repaire surgery

Assessing the effect of oral pregabalin in reducing pain after inguinal hernia repaire surgery

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20221126056613N3
Enrollment
64
Registered
2023-04-19
Start date
2023-04-20
Completion date
Unknown
Last updated
2023-05-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

inguinal hernia. Unilateral inguinal hernia, without obstruction or gangrene

Interventions

Intervention 1: Intervention group: In the pregabalin group, a 300 mg dose of oral pregabalin in two 150 mg capsules will be given to all participants 2 hours before surgery. They will then receive 15

Sponsors

Oroumia University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 18-65 aged men with unilateral indirect inguinal hernia Having a body mass index between 20-29 undergoing surgery by covering hernia sac with mersilene mesh

Exclusion criteria

Exclusion criteria: History of underlying diseases (diabetes, peptic ulcer, gastritis, renal failure) Drug abusers Neuropsychiatric drug users Any known psychologic disorder History of allergic reactions to the drug under study Body mass index more than 30 Patients with incarcerated hernia

Design outcomes

Primary

MeasureTime frame
Severity of pain in lying position. Timepoint: At 4, 12 and 24 hours after surgery. Method of measurement: Visual Analogue Scale.;Severity of pain while walking. Timepoint: At 4, 12 and 24 hours after surgery. Method of measurement: Visual Analogue Scale.;The consumption of opioids for pain after surgery. Timepoint: Up to 24 hours after the surgery. Method of measurement: Based on milligrams.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Akbar Nasir

Oroumia University of Medical Sciences

Nasiriali7@gmail.com+98 44 3345 7286

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026