Condition 1: pre-diabetic state. Condition 2: pre-diabetic state. Impaired fasting glucose Impaired glucose tolerance (oral)
Conditions
Interventions
Intervention 1: Intervention group: Pre diabetic patients receiving probiotic medicine under trade name Biodiab ,a product of Novagen pharmaceutical company with Tekgene Holding, every 12 hou
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: FBS 100-125 mg/dl Impaired OGTT test 2hours after using 75 grams of oral glucose
Exclusion criteria
Exclusion criteria: pregnant women Chronic alcohol consumption Patients with inflammatory bowel disease Patients with Live Cirrhosis Antibiotic usage during the study Patients with celiac disease Probiotic usage during 30 days before the study Usage of Metformin , anti diabetic agent or herbal medicine Corticosteroids usage
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fasting plasma glucose. Timepoint: Before the study and 90 days after intervention. Method of measurement: Photometric method auto analyzer.;Blood sugar two hours after a meal. Timepoint: Before the study and 90 days after intervention. Method of measurement: Photometric method auto analyzer. | — |
Secondary
| Measure | Time frame |
|---|---|
| Body weight. Timepoint: Before the study and 90 days after the intervention. Method of measurement: Body weight scale.;Systolic blood pressure. Timepoint: Before the study and 90 days after the intervention. Method of measurement: Mercury pressure gauge.;Diastolic blood pressure. Timepoint: Mercury pressure gauge. Method of measurement: Before the study and 90 days after the intervention.;Body mass index. Timepoint: Before the study and 90 days after the intervention. Method of measurement: Calculator.;Total Cholesterol. Timepoint: Before the study and 90 days after the intervention. Method of measurement: colorimetric method with auto-analyzer.;Low Density Lipoprotein. Timepoint: Before the study and 90 days after the intervention. Method of measurement: Enzymatic method with auto analyzer.;Serum High Density Lipoprotein. Timepoint: Before the study and 90 days after the intervention. Method of measurement: Enzymatic assay with autoanalyser.;Serum Triglycerides. Timepoint: Before the study and 90 days after the intervention. Method of measurement: Enzymatic assay with autoanalyser.;HbA1c. Timepoint: Before the study and 90 days after the intervention. Method of measurement: Chromatography.;High sensitive C-Reactive Protein. Timepoint: Before the study and 90 days after the intervention. Method of measurement: Turbidimetric Method. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSeyyed Mahmoud Motalebi
Shahid Beheshti University of Medical Sciences
Outcome results
None listed