reduce pain after laparoscopic gynecological procedures

The effect of intraperitoneal spillage of rupivacaine and ketamine in combination with lung recruitment to reduce pain after laparoscopic gynecological procedures

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20221117056529N1

Enrollment

Registered

2023-03-10

Start date

2023-02-09

Completion date

Unknown

Last updated

2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The effects of the combination of ropivacaine and ketamine, pain reduction, laparoscopic surgeries for women. Complication of surgical and medical care, unspecified

Interventions

Intervention 1: Intervention group: 50 women who have undergone laparoscopic surgery will be injected with ropivacaine 0.2% and ketamine 0.5 mg/kg in a total volume of 50 cc by the surgeon into the in

Eligibility

Sex/Gender

Female

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: II or I ASA class , candidates for laparoscopic surgery for women in the age range of 18-60 years in Al-Zahra Hospital, Tabriz Patient consent to enter the study

Exclusion criteria

Exclusion criteria: The existence of any contraindications to the use of ropivacaine and other local anesthetics The presence of any contraindications for ketamine use: history of seizures, psychological disorders, hypertension, high intracerebral pressure, etc. Hypersensitivity to ropivacaine or other local anesthetics and ketamine Concomitant systemic diseases such as any history of cardiovascular, pulmonary, liver, kidney, etc. Presence of chronic pain in the patient Addiction to the use of painkillers and drugs Patient dissatisfaction

Design outcomes

Primary

Measure	Time frame
The percentage of people in whom abdominal and shoulder pain has decreased after laparoscopic surgeries. Timepoint: Upon entering the operating room, standard monitoring including NIBP, HR, RR, ECG, SPO2, and ETCo2 is done and will continue. The severity of shoulder and abdominal pain is recorded every 15 minutes until the patient's complete recovery and delivery to the ward. Method of measurement: The severity of shoulder and abdominal pain, based on VAS score and degree of sedation according to Ramsay sedation score, is recorded every 15 minutes until the patient's complete recovery and delivery to the ward.	—

Measure

Time frame

The percentage of people in whom abdominal and shoulder pain has decreased after laparoscopic surgeries. Timepoint: Upon entering the operating room, standard monitoring including NIBP, HR, RR, ECG, SPO2, and ETCo2 is done and will continue. The severity of shoulder and abdominal pain is recorded every 15 minutes until the patient's complete recovery and delivery to the ward. Method of measurement: The severity of shoulder and abdominal pain, based on VAS score and degree of sedation according to Ramsay sedation score, is recorded every 15 minutes until the patient's complete recovery and delivery to the ward.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactReyhane Abri

Tabriz University of Medical Sciences

reyhane.abri@gmail.com+98 41 3553 9160

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026