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Evaluation of the effectiveness of Metformin and Curcumin in pcos

Evaluation of the effectiveness of Metformin and Curcumin in laboratory criteria in patients with polycystic ovary syndrome

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20221117056528N1
Enrollment
200
Registered
2022-11-29
Start date
2022-11-26
Completion date
Unknown
Last updated
2023-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Polycystic Ovarian Syndrom. Endocrine, nutritional and metabolic diseases

Interventions

Intervention 1: The first intervention group: 50 patients with polycystic ovary syndrome who were given metformin tablets 500 mg every 8 hours from Dineh Iran for three months. Intervention 2: Interve

Sponsors

Zahedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Women with polycystic ovarian syndrom based on the diagnostic criteria of rotterdam including ultrasound examination and symptoms of hyperandrogenism and menstural disorders and ruling out other endocrine disorderssuch as hyperprolactinemia,increase in the thickness of the outer layer of the ovary,cushing syndrom,acromegaly,androgen producing tumors and CAH

Exclusion criteria

Exclusion criteria: Cardiovascular disease Hepatic disease Renal disease Thyroid disease Sever glucose intolerance User of vitamine and mineral supplementary User of weight reducer drugs

Design outcomes

Primary

MeasureTime frame
Lipid profile level. Timepoint: First and three months after the study. Method of measurement: with laboratory sampling in mg/dL.;Hormone profile levels such as testosterone and luteinizing hormone and Follicle-stimulating Hormone. Timepoint: First and three months after the study. Method of measurement: with laboratory sampling in IU/l.;Fasting blood sugar and insulin levels and HOMA-IR. Timepoint: First and three months after the study. Method of measurement: with laboratory sampling in mg/dL.;Average anthropometric indices such as waist circumference and hip circumference and body mass index. Timepoint: First and three months after the study. Method of measurement: By measuring weight in kilograms and height in centimeters.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Feghhi

Zahedan University of Medical Sciences

hfeghhi93@gmail.com054333721514

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026