Melasma skin patients. Chloasma
Conditions
Interventions
Intervention 1: Intervention group: the dressing is used in the form of a sheet (spanless fabric) on which we add a bioactive solution containing 30 mg of chitosan nanocarrier containing glabridine co
Sponsors
Ilam University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
20 Years to 65 Years
Inclusion criteria
Inclusion criteria: Female patients with melasma Age 20 – 65 years Skin type Fitzpatrick II_ V Not receiving treatment within the past month Not taking hormonal medications such as testosterone
Exclusion criteria
Exclusion criteria: Recipients of systemic corticosteroids or hormonal therapies Systemic diseases associated with facial pigmentation, such as diabetes, Addison's disease, hemochromatosis, and liver, kidney, and thyroid problems Patients with photosensitivity disorders, eczema, and dermatitis Psychiatric illnesses Personal or family history of skin cancer
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin color. Timepoint: At the beginning of the intervention and then once a week. Method of measurement: Darkness of the skin, the presence of dark spots. | — |
Secondary
| Measure | Time frame |
|---|---|
| Involved area such as forehead, left malar, right malar, chin. Timepoint: It measured on the first day and then every two weeks. Method of measurement: View.;The rate of recovery of lesions. Timepoint: It is measured every two weeks. Method of measurement: View.;The satisfaction score of using the mask. Timepoint: End of study. Method of measurement: The questionnaire of Lai et al. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMohammad Hossein Haddadi
Ilam University of Medical Sciences
Outcome results
None listed