Comparison of the effects of ketamine and paracetamol on nausea and vomiting after hysterectomy

Comparing the effect of intravenous combined Paracetamol (Apotel) and Ketamine on postoperative nausea and vomiting in patients candidating hysterectomy

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20221111056474N1

Enrollment

114

Registered

2022-12-09

Start date

2022-12-22

Completion date

Unknown

Last updated

2023-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nausea and vomiting after hysterectomy. Nausea and vomiting

Interventions

Intervention 1: Intervention group 1: After induction of anesthesia in all patients, in the first intervention group, in the last 15 minutes of the operation, an amount of one gram of Apotel (Kobel Da

Eligibility

Sex/Gender

Female

Age

25 Years to 65 Years

Inclusion criteria

Inclusion criteria: Candidate patients for elective hysterectomy General anesthesia Receiving opioids after surgery Age 25 to 65 years

Exclusion criteria

Exclusion criteria: Allergy to any of the drugs used in the study History of mental illnesses

Design outcomes

Primary

Measure	Time frame
Nausea and vomiting. Timepoint: 4, 6, 12, and 24 hours after hysterectomy surgery. Method of measurement: Post-operative nausea and vomiting scoring table.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactParand Pirouzi

Arak University of Medical Sciences

Parandpirouzi1@gmail.com+98 86 3417 3034

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026