knee osteoarthritis. Osteoarthritis of knee
Conditions
Interventions
Intervention 1: Intervention group: The group that received 25% dextrose hyper-tonic intra-articularly under ultrasound guidance. Intervention 2: Control group: The group that received normal saline
Sponsors
Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
55 Years to 75 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: aged 55 to75 years; both genders; knee radiography anterior standing view have been for the last one month; have symptoms of osteoarthritis include pain, limitation in knee range of motion , and knee joint dryness for at least a month without any extra-articular involvement.
Exclusion criteria
Exclusion criteria: Inflammatory and vascular collagen diseases such as lupus and suspected knee infection, patients with coagulation disorders, patients with active lumbosacral radiculopathy and severe deformity of the spine and lower limbs, peripheral and central nervous system disorders, pregnancy, diabetes, history of surgery on the knee, injection of steroid drugs in the last two months or intra-articular injection of hyaluronic acid in the last 12 months or replacement of the knee joint, use of opioid drugs, body mass index over 40
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain scale. Timepoint: Just before the intervention & 2,4,8 weeks later. Method of measurement: Visual Analogue Scale,Western Ontario and McMaster Universities Arthritis Index (WOMAC).;Knee flexion degree. Timepoint: Just before the intervention & 2,4,8 weeks later. Method of measurement: goniometry. | — |
Secondary
| Measure | Time frame |
|---|---|
| Functional limitation. Timepoint: Just before the intervention & 2,4,8 weeks later. Method of measurement: Oxford knee score and Western Ontario and McMaster Universities Arthritis Index (WOMAC). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNafiseh Birang
Shiraz University of Medical Sciences
Outcome results
None listed