Endometriosis. Endometriosis
Conditions
Interventions
Intervention 1: Control group: Control group: control group (dienogest and placebo) will receive a dose of 2 mg of dienogest daily along with placebo. Intervention 2: Intervention group: Intervention
Sponsors
Zahedan University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: Women aged 18 to 45 years experiencing pain associated with endometriosis proven by ultrasound and examination and history No previous history of using hormonal agents Candidate to receive dinogest
Exclusion criteria
Exclusion criteria: Pregnancy or breastfeeding Amenorrhea The need for surgery after the intervention Previous use of hormonal agents (such as GnRH agonists for 6 months, progestins, dienogest or danazol for 3 months or oral contraceptives for 1 month before the intervention) Abnormal findings in women's examination Abnormal cervical cytology smear in the last 3 months Taking narcotic painkillers before surgery on a daily basis for 2 weeks before surgery Additional surgeries performed or malignancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Score Of The Quality of life questionnaire. Timepoint: At the beginning of the study (before the start of the intervention) and 2 months later. Method of measurement: Specific Questionnaire of Quality of Life in Endometriosis Patient(Endometriosis Health Profile-30).;Sexual performance score in the questionnaire. Timepoint: At the beginning of the study (before the start of the intervention) and 2 months later. Method of measurement: Female Sexual Function index.;Endometrioma lesion Size. Timepoint: At the beginning of the study (before the start of the intervention) and 2 months later. Method of measurement: Ultrasound and Medical Examination.;Pain Score in the Questionnaire. Timepoint: At the beginning of the study (before the intervention) and 2 months later. Method of measurement: Pain Visual Analog Scale Questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain Score in the Questionnaire. Timepoint: At the beginning of the study (before the intervention) and 2 months later. Method of measurement: Pain Visual Analog Scale Questionnaire.;Sexual performance score in the questionnaire. Timepoint: At the beginning of the study (before the intervention) and 2 months later. Method of measurement: Female Sexual Function Index.;Quality of life score in the questionnaire. Timepoint: At the beginning of the study (before the intervention) and 2 months later. Method of measurement: Specific Questionnaire of Quality of life in Endometriosis Patient(Endometriosis Health Profile-30).;Endometrioma lesion size. Timepoint: At the beginning of the study (before the intervention) and 2 months later. Method of measurement: Ultrasound and medical examination. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMahjob Sargazi Taghazi
Zahedan University of Medical Sciences
Outcome results
None listed