choledocholithiasis with obstruction. Other cholelithiasis with obstruction
Conditions
Interventions
Intervention 1: Intervention group: Group NEB-DEX will receive nebulized dexmedetomidine 1 µg/kg diluted in normal saline (0.9%) to a volume of 5 ml 30 minutes prior to induction of anesthesia. Interv
Sponsors
Tata Main Hospital, Jamshedpur
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Patient undergoing procedural sedation for Endoscopic retrograde cholangio- pancreaticography ASA physical status 1- 3 AGE 18-65 Years
Exclusion criteria
Exclusion criteria: Patient refusal allergy to study drugs Heart rate less than 50/minute Patient on beta blockers Hemodynamically unstable or shock. oxygen saturation less than 95 % on room air Hepatic or renal failure Second degree or third degree heart block BMI > 36 kg/m2
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Propofol consumption per unit time. Timepoint: At the end of procedure. Method of measurement: Propofol consumption will be calculated by sum of amount consumed by infusion and rescue bolus doses of propofol. It will be divided by duration of infusion to calculate per unit time propofol consumption. | — |
Secondary
| Measure | Time frame |
|---|---|
| Patient satisfaction score. Timepoint: at the end of procedure. Method of measurement: Patient satisfaction will be assessed using 5 point Gloucester Comfort Score.;Incidence of Adverse event( Desaturation, hypotension and bradycardia). Timepoint: At the end of procedure. Method of measurement: Hypotension will be defined by blood pressure falling more than 20 % of baseline as measured by sphygmomanometer. Bradycardia will be counted if heart rate is less than 50 during the procedure. If saturation fall below 95 during procedure, it will be counted as desaturation episode. | — |
Countries
India
Contacts
Public ContactDr Rishi Anand
Tata Main Hospital, Jamshedpur
Outcome results
None listed