Effect of hyperbaric Ropivacine in comparison to Bupivacaine for spinal anaesthesia

A prospective randomized controlled study comparing 0.75% hyperbaric ropivacaine with 0.5% hyperbaric bupivacaine in spinal anesthesia for elective caesarean delivery

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20221109056455N1

Enrollment

Registered

2023-07-25

Start date

2023-08-01

Completion date

Unknown

Last updated

2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Delivery by elective Caesarian section. Single delivery by elective caesarean section

Interventions

Intervention 1: Group B. 2.6 ml of Bupivacaine 0.5 % heavy intrathecal. Intervention 2: Group R : 2.6 ml of Ropivacaine 0.75 % heavy intrathecal.

Eligibility

Sex/Gender

Female

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: ASA physical status 1 and 2 Pregnant adults for elective caesarean section

Exclusion criteria

Exclusion criteria: Allergy to Ropivacaine or Bupivacaine Infection at the site for spinal anaesthesia Patient with evidence of foetal distress Short stature (150 cm) Tall stature (>180 cm) Obesity(BMI>30) Patient with an obstetrical complication (multiple gestations, bleeding, gestational hypertensive diseases) Psychiatric or seizure disorder Bleeding disorder Cardiac disease

Design outcomes

Primary

Measure	Time frame
Duration of motor blockade monitored by Bromage scale. Timepoint: 30 min. Method of measurement: Bromage score.	—

Secondary

Measure	Time frame
Onset of sensory blockade. Timepoint: every 2 minutes after spinal block. Method of measurement: pin prick method.;Onset of motor blockade. Timepoint: every 2 minutes after spinal block. Method of measurement: Modified Bromage score.	—

Countries

India

Contacts

Public ContactDr Gunjan Wadhwa

Tata Main Hospital

wadhwagunjan7@gmail.com009198368618827

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026