Comparison of aminophylline infusion with dopamine infusion in patients with kidney dysfunction caused by traumatic brain injuries.

Comparative study of aminophylline infusion with dopamine infusion in traumatic brain injury patients with renal impairment

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20221108056446N8

Enrollment

Registered

2024-05-25

Start date

2024-06-11

Completion date

Unknown

Last updated

2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Acute kidney injury. Condition 2: Traumatic brain injury. Acute kidney injury Diffuse traumatic brain injury

Interventions

Intervention 1: Intervention group 1: Receive aminophylline at a dose of 0.2 mg/kg/h. Intervention 2: Intervention group 2: Receive dopamine at a dose of 2 µg/kg/min. Intervention 3: Control group: Re

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Confirmed Traumatic brain injury by neurological surgeon TBI induced acute kidney injury

Exclusion criteria

Exclusion criteria: Hemodynamic instability Contraindication for of aminophylline or dopamine administration

Design outcomes

Primary

Measure	Time frame
Urinary output. Timepoint: 24 hours after injection. Method of measurement: Urine collection.;BUN level. Timepoint: 24 hours after injection. Method of measurement: Blood test.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyed Taghi Hashemi

Esfahan University of Medical Sciences

st_hashemi@med.mui.ac.ir+98 31 3233 0091

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026