medication related osteonecrosis of the jaw. Osteonecrosis due to drugs
Conditions
Interventions
Intervention group: Antibiotics co-amoxiclav 625 mg three times a day and metronidazole 250 mg three times a day are prescribed from two days before surgery to 7 days after. Then low-level laser two s
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients who are diagnosed with stage 1 and 2 drug-related osteonecrosis of the jaw based on their history and clinical symptoms (individuals who have not improved for more than 8 weeks after identification of exposed bone, have a history of taking bisphosphonates or similar drugs, and have not undergone radiotherapy). Have a history of bisphosphonate/denosumab use. The patient has not received surgical treatment to improve their lesion in the previous 6 months.
Exclusion criteria
Exclusion criteria: Failure to visit regularly for treatment protocol The patient's malignancy is in an active stage Unwillingness to continue treatment Intolerance to medication Patients with stage 3 drug-induced osteonecrosis of the jaw based on history and clinical symptoms Death Stage III patients due to differences in type of surgery and treatment algorithm
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Wound healing. Timepoint: Twice a week for three months after surgery. Method of measurement: Patient examination. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactBizhan Movahedian Atar
Esfahan University of Medical Sciences
Outcome results
None listed