Comparison of the effectiveness of Cinnarizine V/S Topiramate in migraine prophylaxis of children

Comparison of the effectiveness of Cinnarizine V/S Topiramate in migraine prophylaxis of children referred to pediatric neurology clinic

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20221108056444N1

Enrollment

Registered

2023-02-12

Start date

2022-09-23

Completion date

Unknown

Last updated

2023-03-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Migraine. Migraine

Interventions

Intervention 1: The intervention in the present study will be the administration of two drugs, cinnarizine and topiramate. The drug cinnarizine in the form of tablets with a dose of 25 mg will be admi

Eligibility

Sex/Gender

All

Age

6 Years to 15 Years

Inclusion criteria

Inclusion criteria: Children with migraine The need for prophylactic treatment Age 6-15 years

Exclusion criteria

Exclusion criteria: Patients with advanced migraine who need drugs other than painkillers Previous history of receiving prophylactic treatment Abnormal brain and nerve imaging and special conditions such as seizures, epilepsy or the presence of contraindications for the use of cinnarizine and topiramate

Design outcomes

Primary

Measure	Time frame
Headache. Timepoint: At the beginning of the study, 1, 3, 6, 9, and 12 weeks after the start of treatment. Method of measurement: Migraine Questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAisan Abazarlou

Oroumia University of Medical Sciences

draisanabazarlou@yahoo.com+98 44 3223 7077

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: May 11, 2026