Esmolol and Labetalol in cataract surgury in patient with chronic hypertension.

A comparative study of labetalol and esmolol intravenous infusion in the prevention of cardiovascular complications and ischemic changes in patients with chronic hypertension during cataract surgery under local anesthesia with sedation

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20221108056442N1

Enrollment

Registered

2022-11-26

Start date

2022-12-22

Completion date

Unknown

Last updated

2023-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiovascular complications and ischemic changes in patients with chronic hypertension during cataract surgery.

Interventions

Intervention 1: Intervention group:0.5 mg/kg of intravenous osmolol, whose volume will be increased to 20 cc by sterile normal saline, 5 minutes before the injection of sedative and sedative drugs and

Eligibility

Sex/Gender

All

Age

65 Years to No maximum

Inclusion criteria

Inclusion criteria: Candidate patients for cataract surgery Patients over 65 years old

Exclusion criteria

Exclusion criteria: History of drug allergy Addiction

Design outcomes

Primary

Measure	Time frame
Heart Rate. Timepoint: Before the start of the operation, 5 minutes after the start of the operation, every 15 minutes until the end of the operation. Method of measurement: Cardiac Monitor device.;Systolic Blood Pressure. Timepoint: Before the start of the operation, 5 minutes after the start of the operation, every 15 minutes until the end of the operation. Method of measurement: In millimeteres of mercury using a Calibrated Barometer.;Diastolic Blood pressure. Timepoint: Before the start of the operation, 5 minutes after the start of the operation, every 15 minutes until the end of the operation. Method of measurement: In millimeteres of mercury using a Calibrated Barometer.;Percentage of oxygen Saturation. Timepoint: Before the start of the operation, 5 minutes after the start of the operation, every 15 minutes until the end of the operation. Method of measurement: Pulse oximeter.	—

Measure

Time frame

Heart Rate. Timepoint: Before the start of the operation, 5 minutes after the start of the operation, every 15 minutes until the end of the operation. Method of measurement: Cardiac Monitor device.;Systolic Blood Pressure. Timepoint: Before the start of the operation, 5 minutes after the start of the operation, every 15 minutes until the end of the operation. Method of measurement: In millimeteres of mercury using a Calibrated Barometer.;Diastolic Blood pressure. Timepoint: Before the start of the operation, 5 minutes after the start of the operation, every 15 minutes until the end of the operation. Method of measurement: In millimeteres of mercury using a Calibrated Barometer.;Percentage of oxygen Saturation. Timepoint: Before the start of the operation, 5 minutes after the start of the operation, every 15 minutes until the end of the operation. Method of measurement: Pulse oximeter.

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Secondary

Measure	Time frame
Hypertension. Timepoint: Before the start of the operation, 5 minutes after the start of the operation, every 15 minutes until the end of the operation. Method of measurement: In millimeteres of mercury using a Calibrated Barometer.;Hypotension. Timepoint: Before the start of the operation, 5 minutes after the start of the operation, every 15 minutes until the end of the operation. Method of measurement: In millimeteres of mercury using a Calibrated Barometer.;Tachycardia. Timepoint: Before the start of the operation, 5 minutes after the start of the operation, every 15 minutes until the end of the operation. Method of measurement: Cardiac Monitor device.;Bradycardia. Timepoint: Before the start of the operation, 5 minutes after the start of the operation, every 15 minutes until the end of the operation. Method of measurement: Cardiac Monitor device.	—

Measure

Time frame

Hypertension. Timepoint: Before the start of the operation, 5 minutes after the start of the operation, every 15 minutes until the end of the operation. Method of measurement: In millimeteres of mercury using a Calibrated Barometer.;Hypotension. Timepoint: Before the start of the operation, 5 minutes after the start of the operation, every 15 minutes until the end of the operation. Method of measurement: In millimeteres of mercury using a Calibrated Barometer.;Tachycardia. Timepoint: Before the start of the operation, 5 minutes after the start of the operation, every 15 minutes until the end of the operation. Method of measurement: Cardiac Monitor device.;Bradycardia. Timepoint: Before the start of the operation, 5 minutes after the start of the operation, every 15 minutes until the end of the operation. Method of measurement: Cardiac Monitor device.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDarioush Moradi Farsani

Esfahan University of Medical Sciences

Dmoradi@med.mui.ac.ir+98 31 4754 7767

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026