Skip to content

Comparison of efficacy with haloperidol versus ondansetron on postoperative nausea and vomiting in laparoscopic sleeve gastrectomy

Comparison of premedication efficacy with haloperidol versus ondansetron on postoperative nausea and vomiting in adult patient following laparoscopic sleeve gastrectomy

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20221108056438N1
Enrollment
60
Registered
2022-12-11
Start date
2022-12-02
Completion date
Unknown
Last updated
2023-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

laparoscopic sleeve gastrectomy. Acquired absence of stomach [part of]

Interventions

Intervention 1: Intervention group 1: Group (A) patients, after induction, 0.05 mg of haloperidol per kilogram (maximum dose of 30 mg) will be injected intravenously within 5 minutes. Intervention 2:

Sponsors

Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Informed consent All patients who are candidates for LSG surgery ASA Class I and II between 18 and 60 years old

Exclusion criteria

Exclusion criteria: Patients with an underlying disease that is not currently under control. Patients who have a history of allergy to haloperidol or ondansetron. Patients who have a history of alcohol consumption, use of antidepressants and drug addiction (if they become symptomatic by not taking) pregnant women Lactating women People suffering from anxiety disorders, restlessness, tremors, convulsions, tinnitus Cases in which the surgeon decides to change the surgical procedure for any reason during the operation Patients who have a history of bradycardia, hypotension, cardiovascular collapse and respiratory arrest. Patients who have used an anti-nausea and vomiting agent within 24 hours before surgery.

Design outcomes

Primary

MeasureTime frame
Nausea and vomiting. Timepoint: Every 15 minutes in recovery and every hour in the ward. Method of measurement: They will be evaluated based on VAS or Visual Analogue Scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli karami

Shiraz University of Medical Sciences

Karamiali@sums.ac.ir+98 71 3647 4270

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026