Preterm labour. Preterm labor
Conditions
Interventions
Intervention 1: Intervention group: Vaginal progesterone group, daily one suppository of 400 mg of vaginal progesterone suppository and three oral pills of the same placebo (vitamin B6). Intervention
Sponsors
Gorgan University of Medical Sciences
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Cervical length less than 25 mm, measured by transvaginal ultrasound Singleton pregnancy Refer to the center at the age of pregnancy between 6 and 18 weeks Any evidence of threatened abortion( vaginal bleeding and bloody vaginal discharge) in the first half of pregnancy Willingness and written consent to enter the study Follow-up and regular referrals for pregnancy care
Exclusion criteria
Exclusion criteria: Multiple pregnancy Any uncontrolled systemic disease(diabete, blood pressure, kidney, liver, etc.) History of consuming alcoholic beverages or drug or drug abuse Absence of gestational sac in the fifth week Lack of yolk sac in 5.5 to 6 weeks of pregnancy Absence of fetus in 6-6.5 weeks of pregnancy Absence of fetal heartbeat in weeks 16 to 24 Having a history of preterm delivery Having a pair of umbilical cords confirmed by transvaginal ultrasound History of surgery on the cervix Fetal and uterine anomalies
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cervical length. Timepoint: 1, 5, 9 weeks after starting treatment and immediately after delivery. Method of measurement: Vaginal ultrasound. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMahboobeh Khajehpour
Gorgan University of Medical Sciences
Outcome results
None listed