Effectiveness of platelet-rich plasma injection in treatment of stress urinary incontinence.

Evaluating the effectiveness of pelvic floor biofeedback combined with autologous platelet-rich plasma injection in comparison to biofeedback as a monotherapy in rehabilitation of women with stress urinary incontinence.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20221106056413N1

Enrollment

Registered

2023-01-24

Start date

2023-03-21

Completion date

Unknown

Last updated

2023-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stress urinary incontinence. Stress incontinence (female) (male)

Interventions

Intervention 1: Intervention group: 24 patients undergoing pelvic floor muscle rehabilitation treatment as 35-minute sessions, once a week, including 20 minutes of electrical stimulation with a vagina

Eligibility

Sex/Gender

Female

Age

20 Years to 70 Years

Inclusion criteria

Inclusion criteria: Women with clinical symptoms of urinary incontinence. Age 35-55 patients opting for non-surgical management.

Exclusion criteria

Exclusion criteria: Stage>II prolapse Cervical dysplasia and malignancy Recurrent urinary tract infection Pelvic reconstruction surgery Pregnancy Abnormal uterine bleeding Anti-platelet drug medication Psychological disorders History of surgery due to urinary incontinence Uncontrolled diabetes Neurogenic urinary incontinence Urge urinary incontinence

Design outcomes

Primary

Measure	Time frame
Stress urinary incontinence. Timepoint: The effectiveness of platelet-rich plasma injection and pelvic floor biofeedback after 4 weekly sessions of biofeedback and 3 monthly sessions of PRP shots on women suffering from stress urinary incontinence. Method of measurement: International Consultation on Incontinence Questionnaire- Female Lower Urinary Tract Symptom (ICIQ-FLUTS) long form and short form.	—

Measure

Time frame

Stress urinary incontinence. Timepoint: The effectiveness of platelet-rich plasma injection and pelvic floor biofeedback after 4 weekly sessions of biofeedback and 3 monthly sessions of PRP shots on women suffering from stress urinary incontinence. Method of measurement: International Consultation on Incontinence Questionnaire- Female Lower Urinary Tract Symptom (ICIQ-FLUTS) long form and short form.

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Secondary

Measure	Time frame
Sexual Function. Timepoint: The effectiveness of platelet-rich plasma injection and pelvic floor biofeedback after 4 weekly sessions of biofeedback and 3 monthly sessions of PRP shots on sexual function of women suffering from stress urinary incontinence. Method of measurement: Female Sexual Function Index Pelvic incontinence Sexual Questionnaire-12.;Quality of life. Timepoint: The effectiveness of platelet-rich plasma injection and pelvic floor biofeedback after 4 weekly sessions of biofeedback and 3 monthly sessions of PRP shots on quality of life of women suffering from stress urinary incontinence. Method of measurement: International Consultation on Incontinence Questionnaire- Quality of Life (ICIQ-QOL).	—

Measure

Time frame

Sexual Function. Timepoint: The effectiveness of platelet-rich plasma injection and pelvic floor biofeedback after 4 weekly sessions of biofeedback and 3 monthly sessions of PRP shots on sexual function of women suffering from stress urinary incontinence. Method of measurement: Female Sexual Function Index Pelvic incontinence Sexual Questionnaire-12.;Quality of life. Timepoint: The effectiveness of platelet-rich plasma injection and pelvic floor biofeedback after 4 weekly sessions of biofeedback and 3 monthly sessions of PRP shots on quality of life of women suffering from stress urinary incontinence. Method of measurement: International Consultation on Incontinence Questionnaire- Quality of Life (ICIQ-QOL).

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactTayebeh Sadat Salehi Rihani

Shiraz University of Medical Sciences

tayebe.sadat.s.r@gmail.com+98 21 2645 2587

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026