Comparison of the effect of exercise training on bone metabolism in adolescent boy

Comparison of the effect of 12 weeks of plyometric and HICT training on serum levels of FGF23, KLOTHO, and Some markers related to bone metabolism in adolescent boy

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20221102056381N1

Enrollment

Registered

2023-06-24

Start date

2023-04-30

Completion date

Unknown

Last updated

2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bone Density.

Interventions

Intervention 1: Intervention group 1: HICT exercise protocol is performed three days a week for 12 weeks. The intensity of the exercises will be gradually increased by using the methods of increasing

Eligibility

Sex/Gender

Male

Age

13 Years to 15 Years

Inclusion criteria

Inclusion criteria: Male teenagers Aged 13-15 years

Exclusion criteria

Exclusion criteria: Any type of disease such as anemia, obesity, diabetes, heart disease Using any type of special medicine Participating in regular sports activities in the last 6 months

Design outcomes

Primary

Measure	Time frame
Serum level of FGF23. Timepoint: Before and after 12 weeks of plyometric and HICT training. Method of measurement: Eliza kit (BioSwamp Company, NY, USA).;Serum level of aKlotho. Timepoint: Before and after 12 weeks of plyometric and HICT training. Method of measurement: Using the ELISA kit.;Serum level of GH. Timepoint: Before and after 12 weeks of plyometric and HICT training. Method of measurement: radium kit.;SERUM LEVEL OF IGF-1. Timepoint: Before and after 12 weeks of plyometric and HICT training. Method of measurement: DRG IGF-11600 enzyme immunoassay kit.;BMD. Timepoint: Before and after 12 weeks of plyometric and HICT training. Method of measurement: Dual-energy X-ray absorptiometry (DEXA).;BMC. Timepoint: Before and after 12 weeks of plyometric and HICT training. Method of measurement: Dual-energy X-ray absorptiometry (DEXA).	—

Measure

Time frame

Serum level of FGF23. Timepoint: Before and after 12 weeks of plyometric and HICT training. Method of measurement: Eliza kit (BioSwamp Company, NY, USA).;Serum level of aKlotho. Timepoint: Before and after 12 weeks of plyometric and HICT training. Method of measurement: Using the ELISA kit.;Serum level of GH. Timepoint: Before and after 12 weeks of plyometric and HICT training. Method of measurement: radium kit.;SERUM LEVEL OF IGF-1. Timepoint: Before and after 12 weeks of plyometric and HICT training. Method of measurement: DRG IGF-11600 enzyme immunoassay kit.;BMD. Timepoint: Before and after 12 weeks of plyometric and HICT training. Method of measurement: Dual-energy X-ray absorptiometry (DEXA).;BMC. Timepoint: Before and after 12 weeks of plyometric and HICT training. Method of measurement: Dual-energy X-ray absorptiometry (DEXA).

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Secondary

Measure	Time frame
SERUM LEVEL OF CALSITERIOL. Timepoint: Before and after 12 weeks of plyometric and HICT training. Method of measurement: ELISA TEST.;SERUN LEVEL OF PHOSPHATE. Timepoint: Before and after 12 weeks of plyometric and HICT training. Method of measurement: ELISA TEST.;SERUM LEVEL OF CALSIUM. Timepoint: Before and after 12 weeks of plyometric and HICT training. Method of measurement: ELISA TEST.;Serum level of PHEX. Timepoint: Before and after 12 weeks of plyometric and HICT training. Method of measurement: ELISA TEST.;Serun level of PTH. Timepoint: Before and after 12 weeks of plyometric and HICT training. Method of measurement: ELISA TEST.;SeruM level of vitamin D. Timepoint: Before and after 12 weeks of plyometric and HICT training. Method of measurement: Elisa test.;Serum level of DMP1. Timepoint: Before and after 12 weeks of plyometric and HICT training. Method of measurement: Elisa test.	—

Measure

Time frame

SERUM LEVEL OF CALSITERIOL. Timepoint: Before and after 12 weeks of plyometric and HICT training. Method of measurement: ELISA TEST.;SERUN LEVEL OF PHOSPHATE. Timepoint: Before and after 12 weeks of plyometric and HICT training. Method of measurement: ELISA TEST.;SERUM LEVEL OF CALSIUM. Timepoint: Before and after 12 weeks of plyometric and HICT training. Method of measurement: ELISA TEST.;Serum level of PHEX. Timepoint: Before and after 12 weeks of plyometric and HICT training. Method of measurement: ELISA TEST.;Serun level of PTH. Timepoint: Before and after 12 weeks of plyometric and HICT training. Method of measurement: ELISA TEST.;SeruM level of vitamin D. Timepoint: Before and after 12 weeks of plyometric and HICT training. Method of measurement: Elisa test.;Serum level of DMP1. Timepoint: Before and after 12 weeks of plyometric and HICT training. Method of measurement: Elisa test.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactReyhane Shokoohi

Shahrekord University

r.shokoohi2008@yahoo.com+98 38 3232 4407

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026