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Evaluating the effects of empagliflozin in preventing myocardial damage in patients undergoing percutaneous coronary intervention

Evaluating the effects of empagliflozin in preventing myocardial damage in patients undergoing percutaneous coronary intervention: a double-blind randomized clinical trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20221102056378N1
Enrollment
90
Registered
2022-11-07
Start date
2022-11-11
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiovascular disease. Cardiovascular disease, unspecified

Interventions

Intervention 1: Intervention group: The recipient of empagliflozin 25 mg tablets manufactured by Farmashi Pharmaceutical Company, Iran, one day and one to two hours before coronary intervention. Inter

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Age 18-80 years Ischemic heart diseases patients candidate for angioplasty and stentstent insertion Filling of consent form

Exclusion criteria

Exclusion criteria: History of infarction History of open heart surgery in the last 3 months Renal dysfunction Dialysis Failed History of Coronary Angioplasty cardiogenic shock cancer Liver failure Autoimmune disease Pregnancy History of serious allergy to empagliflozin Inability in filling and understanding of the consent form

Design outcomes

Primary

MeasureTime frame
CTnI level. Timepoint: 8 hours and 24 hours after the intervention. Method of measurement: ELISA kits.;Hs-CRP level. Timepoint: 24 hours after the intervention. Method of measurement: ELISA kits.

Secondary

MeasureTime frame
Major Adverse Cardiac Effects. Timepoint: 1 month after hospital discharge. Method of measurement: Follow up by phone.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHosein Behzad Vakilabad

Tabriz University of Medical Sciences

hbehzad.pharma@gmail.com+98 41 3554 1221

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026