gastroesophageal reflux disorder. Gastro-esophageal reflux disease with esophagitis
Conditions
Interventions
Intervention 1: Intervention group: One capsule of placebo half an hour before breakfast, one capsule of coriander after lunch and one capsule of coriander after dinner. Intervention 2: Control group:
Sponsors
Fasa University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Organic causes of indigestion have been ruled out by the doctor. Do not have a history of allergy to medicinal plants used in this study. Not pregnant or breastfeeding and not planning to become pregnant during the study. Do not have chronic liver, kidney or cancer diseases. Not taking anticoagulant drugs such as warfarin, plavix, aspirin and other chemical or herbal drugs that interfere with the studied compound or disrupt the results of the plan. The patient has been diagnosed with GERD by a doctor during endoscopy. Having ROME IV criteria to enter the study
Exclusion criteria
Exclusion criteria: Incidence of drug allergy Diagnosis of organic dyspepsia during study The patient's unwillingness to continue the plan Starting to take drugs such as anticoagulants such as warfarin, Plavix, aspirin and other drugs that interfere with the herbs in the composition or have a possible positive or negative effect on functional indigestion. Pregnancy contracting covid19 or any disease for which the doctor required the patient to withdraw from the plan. The location of the study is the clinic and office of internal medicine and gastroenterology specialists in Fasa city.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quality of life (SF-36 questionnaire). Timepoint: 30, 60 days from the first day of study. Method of measurement: SF-36 questionnaire.;Abdominal bloating intensity and rate, early satiety rate, stomach rumbling rate and burping rate. Timepoint: 30, 60 days from the first day of study. Method of measurement: questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFasa University of Medical Sciences
Fasa University of Medical Sciences
Outcome results
None listed