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The effect of Botox alone with the effect of Botox ) (masport brand)and Profhilo to remove forehead wrinkles

Comparison of the effect of Botulinum toxin(masport brand ) injection along with Profhilo gel with Botulinum toxin (masport brand )injection alone in patients with a request to remove forehead wrinkles

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20221029056334N1
Enrollment
20
Registered
2022-12-11
Start date
2022-12-22
Completion date
Unknown
Last updated
2023-03-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Improve forehead wrinkles.

Interventions

Intervention 1: Intervention group: Intervention group: Botox masport injection will be performed in the first session for the group receiving toxin alone. Intervention 2: Intervention group: The inje

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: In this study, the participants are volunteers who have good general health and, according to the registration researcher, their forehead lines have a score of 2 and above based on MERZscoring.

Exclusion criteria

Exclusion criteria: Pregnancy and breastfeeding History of allergy to Botox and fillers Previous botox injection in the forehead area within the last six months History of laser in the forehead area during the last six months Active infection in the forehead area Intention to use tretinoin or retinoic acid in the next 6 months

Design outcomes

Primary

MeasureTime frame
Depth and number of forehead wrinkles based on Merz score. Timepoint: Measurement of the number and depth of forehead wrinkles before and one month and three months after injections. Method of measurement: Merz scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactGhazal Ghafarzadeh

Tehran University of Medical Sciences

qazalqafffar@gmail.com+98 21 2267 5027

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026