Effect of intravenous Ketamine in reducing postoperative pain

Evaluation of the effect of intravenous Ketamine in reducing postoperative pain in lower limb fracture

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20221029056333N1

Enrollment

Registered

2022-11-02

Start date

2022-11-16

Completion date

Unknown

Last updated

2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lower limb fracture. Lower limb fracture

Interventions

Intervention 1: Intervention group: 0.3 mg/kg (ketamine) is given as an intravenous injection half an hour before induction of anesthesia. Intervention 2: Control group: They will receive an intraveno

Eligibility

Sex/Gender

All

Age

20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Age 20 to 60 years old Lower limb fracture Having consent to enter the study

Exclusion criteria

Exclusion criteria: Patients with a history of psychosis and cognitive disorders Patients with a history of drug addiction Pregnant women

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: In 5 recovery periods, 6 hours, 12 hours and 24 hours after surgery. Method of measurement: Using the VAS scale & record severe pain intensity.	—

Secondary

Measure	Time frame
Nausea. Timepoint: 24 hours after surgery. Method of measurement: By N&V benchmark.;Vomiting. Timepoint: 24 hours after surgery. Method of measurement: By N&V benchmark.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Meysam Mahmodi

Babol University of Medical Sciences

mamodi@gmail.com+98 11 3225 6285

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026