Mucositis caused by radiotherapy.
Conditions
Interventions
Intervention 1: Intervention group: Including 60 patients who receive pomegranate flower mouthwash in the amount of 10 cc 3 times a day. To prepare the product, firstly, pomegranate flower is procured
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: The study of patients with head and neck cancers who are candidates for at least 50 Gy radiotherapy to the oral cavity with or without concurrent chemotherapy after surgery will be included in the study.
Exclusion criteria
Exclusion criteria: Patients who had a history of head and neck radiotherapy, opium addiction or methadone use, active mucosal disease in the radiotherapy area and people under 18 years of age are excluded from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of mucositis according to who definition. Timepoint: Checking the severity of mucositis every week during radiotherapy. Method of measurement: Based on the definition of the severity of mucositis of the World Health Organization. Severity of mucositis based on who definition. Zero grade: The patient has no symptoms. Grade 1: Erythema and mouth burning (brief mucosal inflammation) Grade 2: Erythema and oral ulcers that still have the ability to eat solid foods. (Mild pain that requires painkillers.) Grade 3: Ulcers with extensive erythema who cannot swallow solid food. (Severe pain that requires strong pain relief) Grade 4: Mucositis has become very widespread and has made feeding completely impossible for the person, and at the same time that there is a need for hospitalization for him. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public Contactfatemeh samadi
Tehran University of Medical Sciences
Outcome results
None listed