Preparation and evaluation of a new dressing aim to treat dry socket

Preparation and in-vitro and in-vivo evaluation of a lipid-liquid crystal gel dressing containing eugenol and iodoform aim to treatment of alveolar osteitis

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20221027056320N1

Enrollment

Registered

2022-12-02

Start date

2022-11-19

Completion date

Unknown

Last updated

2023-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

alveolar osteitis (dry socket). Alveolar osteitis , Dry socket

Interventions

Intervention 1: Control group: applying sufficient amount of alveogel manufactured by the Turkish company "Kalsin" in the tooth socket so that it fills the socket and repeating it every 24 hours in ca

Eligibility

Sex/Gender

All

Age

30 Years to 60 Years

Inclusion criteria

Inclusion criteria: Participants' age should be between 18 to 60 years old. Patients suffering from dry socket following a tooth extraction who refer to Mashhad dentistry school. Participants should sign the informed consent.

Exclusion criteria

Exclusion criteria: Smoking or addiction Pregnancy and breastfeeding History of allergy to foods and drugs Suffering from systemic diseases Active infective disease (such as hepatitis , AIDS ,TB) Taking medications which interact with healing process (such as corticosteroids , immunosuppressors , anticancer drugs , anticoagulants) Age under 18 or above 60 years old History of radiotherapy of head and neck region.

Design outcomes

Primary

Measure	Time frame
Measuring patients' pain upon admission (according to VAS) and examining the intensity of pain after applying each type of dressing. Timepoint: At 30, 60 minutes and 6, 12, 24, 48, 72 hours and 7 days after application and it continues on a daily basis, until the patient has pain. Method of measurement: Questionnaire designed based on Visual Analog Scale (VAS).;Checking the number of times the dressing is used. Timepoint: After the complete relief of pain and at the end of the follow-up. Method of measurement: Recording the frequency of dressing use in Excel by the researcher.	—

Measure

Time frame

Measuring patients' pain upon admission (according to VAS) and examining the intensity of pain after applying each type of dressing. Timepoint: At 30, 60 minutes and 6, 12, 24, 48, 72 hours and 7 days after application and it continues on a daily basis, until the patient has pain. Method of measurement: Questionnaire designed based on Visual Analog Scale (VAS).;Checking the number of times the dressing is used. Timepoint: After the complete relief of pain and at the end of the follow-up. Method of measurement: Recording the frequency of dressing use in Excel by the researcher.

—

Secondary

Measure	Time frame
Checking the number of Analgesic used for each patient. Timepoint: After the complete relief of pain and at the end of the follow-up. Method of measurement: Asking the patient and recording in Excel by the researcher.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmirhossein Chavoshi

Mashhad University of Medical Sciences

chavoshia961@mums.ac.ir+98 51 3890 9880

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026