Investigating the effect of conditioning medium in the treatment of alopecia

15- Investigating the safety and effectiveness of the injection of conditioned medium derived from keratinocyte and fibroblast cells forascin compared to platelet rich plasma in the treatment of androgenic alopecia: a blinded randomized controlled interventional study

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20221026056309N1

Enrollment

Registered

2022-11-08

Start date

2022-11-21

Completion date

Unknown

Last updated

2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Androgenic alopecia. Androgenic alopecia

Interventions

Intervention 1: Intervention group: The intervention group is treated with conditioned medium for 4 sessions with 1 month intervals. 4 ml of concentrated culture medium is used for each injection. Inj

Eligibility

Sex/Gender

All

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Men and women with hereditary hormonal hair loss Hamilton score 2-5 in men and Ludwig score 1-3 in women Complete consent of the patient to participate in the plan

Exclusion criteria

Exclusion criteria: Platelet disorders or thrombocytopenia Patients receiving anticoagulants Receiving any topical or systemic medication in the last 3 months for hair loss

Design outcomes

Primary

Measure	Time frame
Number of hairs. Timepoint: At the beginning of the study and 3 and 6 months after the end of the study. Method of measurement: by the hair analyzer.;Hair thickness. Timepoint: At the beginning of the study and 3 and 6 months after the end of the study. Method of measurement: by the hair analyzer.;Patient satisfaction score of treatment. Timepoint: At the beginning of the study and 3 and 6 months after the end of the study. Method of measurement: Using a standard scoring scale.;The doctor's score is based on changing the standard photos. Timepoint: 3 and 6 months after completion of treatment. Method of measurement: Using a standard scoring scale.	—

Measure

Time frame

Number of hairs. Timepoint: At the beginning of the study and 3 and 6 months after the end of the study. Method of measurement: by the hair analyzer.;Hair thickness. Timepoint: At the beginning of the study and 3 and 6 months after the end of the study. Method of measurement: by the hair analyzer.;Patient satisfaction score of treatment. Timepoint: At the beginning of the study and 3 and 6 months after the end of the study. Method of measurement: Using a standard scoring scale.;The doctor's score is based on changing the standard photos. Timepoint: 3 and 6 months after completion of treatment. Method of measurement: Using a standard scoring scale.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactElham Behrangi

Iran University of Medical Sciences

elham.behrangi@gmail.com+98 21 86701

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026