Investigating the effectiveness of anticoagulants compared to aspirin and clopidogrel on disease severity in patients with ischemic stroke.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20221026056307N1

Enrollment

Registered

2023-01-18

Start date

2023-02-20

Completion date

Unknown

Last updated

2023-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cerebral infarction. Cerebral infarction

Interventions

Intervention 1: Intervention group: An enoxaparin group with a therapeutic dose (one mg per body weight) is prescribed in the first 24 hours and then on the second day of starting rivaroxaban with a d

Eligibility

Sex/Gender

All

Age

18 Years to 90 Years

Inclusion criteria

Inclusion criteria: Patients with ischemic stroke without embolic origin Patients aged 18 to 90 years NIHSS less than 15

Exclusion criteria

Exclusion criteria: Patients with hemorrhagic stroke Patients with ischemic stroke of embolic origin Stroke patients with NIHSS scores less than 15

Design outcomes

Primary

Measure	Time frame
MRS scores. Timepoint: 10 days and 3 months after the intervention. Method of measurement: MRS is a commonly used scale for measuring the degree of disability or dependence in the daily activities of people who have suffered a stroke or other causes of neurological disability.A score of 0 is no disability, 5 is disability requiring constant care for all needs; 6 is death.;NIHSS scores. Timepoint: 10 days and 3 months after the intervention. Method of measurement: The NIHSS is composed of 11 items, each of which scores a specific ability between a 0 and 4. For each item, a score of 0 typically indicates normal function in that specific ability, while a higher score is indicative of some level of impairment.The individual scores from each item are summed in order to calculate a patient's total NIHSS score. The maximum possible score is 42, with the minimum score being a 0.	—

Measure

Time frame

MRS scores. Timepoint: 10 days and 3 months after the intervention. Method of measurement: MRS is a commonly used scale for measuring the degree of disability or dependence in the daily activities of people who have suffered a stroke or other causes of neurological disability.A score of 0 is no disability, 5 is disability requiring constant care for all needs; 6 is death.;NIHSS scores. Timepoint: 10 days and 3 months after the intervention. Method of measurement: The NIHSS is composed of 11 items, each of which scores a specific ability between a 0 and 4. For each item, a score of 0 typically indicates normal function in that specific ability, while a higher score is indicative of some level of impairment.The individual scores from each item are summed in order to calculate a patient's total NIHSS score. The maximum possible score is 42, with the minimum score being a 0.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmir Ali Ghahramani

Bojnourd University of Medical Sciences

amirali.ghahremani@yahoo.com+98 58 3151 1421

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026