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Effects of whey protein isolate consumption on patients undergoing cardiac surgery

Evaluating the effects of whey protein isolate on cardiovascular risk factors and quality of life in patients undergoing coronary artery bypass grafting

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20221022056263N1
Enrollment
42
Registered
2023-01-14
Start date
2021-11-15
Completion date
Unknown
Last updated
2023-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

patients undergoing coronary artery bypass grafting. Atherosclerosis of coronary artery bypass graft(s), unspecified, with unspecified angina pectoris

Interventions

Intervention 1: Intervention group: Ten grams of whey protein isolate (once a day) for a period of 14 days will be consumed orally after dissolving in water. Intervention 2: Control group: Three grams

Sponsors

Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 75 Years

Inclusion criteria

Inclusion criteria: patients who are undergoing coronary artery bypass grafting age 30-75 years

Exclusion criteria

Exclusion criteria: heart surgery for the second time simultaneous surgeries (such as heart valve surgery) ejection fraction lower than 30 patients with renal failure patients with liver cirrhosis patients with cancer having metabolic amino acid disorders (such as phenylketonuria) patients with malabsorptive syndrome having celiac disease allergy to milk and dairy products patients with Alzheimer's disease patients with active infection pregnant women lactating women receiving levodopa or albendazole medications

Design outcomes

Primary

MeasureTime frame
Fasting blood glucose. Timepoint: Before the start of intervention and 14 days after it. Method of measurement: colorimetric method.;Serum triglyceride. Timepoint: Before the start of intervention and 14 days after it. Method of measurement: colorimetric method.;Serum total cholesterol. Timepoint: Before the start of intervention and 14 days after it. Method of measurement: colorimetric method.;Low-density lipoprotein cholesterol (LDL-C). Timepoint: Before the start of intervention and 14 days after it. Method of measurement: colorimetric method.;High-density lipoprotein cholesterol (HDL-C). Timepoint: Before the start of intervention and 14 days after it. Method of measurement: colorimetric method.;Serum albumin. Timepoint: Before the start of intervention and 14 days after it. Method of measurement: colorimetric method.;Quality of life determined by MacNew questionnaire. Timepoint: Before the start of intervention and 14 days after it. Method of measurement: MacNew Heart Disease health-related quality of life questionnaire.

Secondary

MeasureTime frame
Atherogenic Index of plasma. Timepoint: Before the start of intervention and 14 days after it. Method of measurement: logarithm of triglyceride (mmol/l) to high-density lipoprotein cholesterol (mmol/l) ratio.;Total cholesterol to high-density lipoprotein cholesterol (HDL-C) ratio. Timepoint: Before the start of intervention and 14 days after it. Method of measurement: total cholesterol divided by high-density lipoprotein cholesterol.;Low-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (LDL-C/HDL-C). Timepoint: Before the start of intervention and 14 days after it. Method of measurement: low-density lipoprotein cholesterol divided by high-density lipoprotein cholesterol.;Non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (non-HDL-C/HDL-C). Timepoint: Before the start of intervention and 14 days after it. Method of measurement: First of all, high-density lipoprotein cholesterol (HDL-C) is subtracted from total cholesterol to determine non-high-density lipoprotein cholesterol (non-HDL-C). Then, non-HDL-C is divided by HDL-C.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Mohammad-Hosseini

Shiraz University of Medical Sciences

maryammh63@yahoo.com+98 71 3735 5041

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026