negative symptoms. Schizophrenia
Conditions
Interventions
Intervention 1: Intervention group: The first group receives 1 mg of B12. Intervention 2: Intervention group: The second group receives 1 mg of folic acid. Intervention 3: Intervention group: third g
Sponsors
University of social welfare and rehabilitation sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 18 to 60 years old who have been treated with antipsychotic drugs for at least 6 months No history of taking vitamins B12 and folic acid in the last 1 month Absence of liver disorders, megaloblastic anemia and special diet , use of other nutritional supplements During the last 1 month Not consuming alcohol and other substances in the last 6 months Absence of pregnancy and breastfeeding negative symptoms
Exclusion criteria
Exclusion criteria: history of taking vitamins B12 and folic acid in the last 1 month liver disorders, megaloblastic anemia and special diet , use of other nutritional supplements During the last 1 month alcohol and other substances in the last 6 months pregnancy and breastfeeding
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| B12-acid folic-negative symptoms. Timepoint: At the beginning of the study and two months after taking B12 and folic acid, the blood level of vitamins will be measured and the SANS questionnaire will be filled. Method of measurement: SCALE FOR THE ASSESSMENT OF NEGATIVE SYMPTOMS/ Blood level of b12 and acid folic. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMahnaz shahali
University of social welfare and rehabilitation sciences
Outcome results
None listed