androgenetic alopecia. Androgenic alopecia
Conditions
Interventions
Intervention 1: Control group: using minoxidil solution 5% with normal saline injection. Intervention 2: Intervention group: using minoxidil 5% solution with the injection of 100 units botulinum toxin
Sponsors
Tehran University of Medical Sciences
Masoondarou pharmaceutical Company MDPC
Eligibility
Sex/Gender
Female
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: Patients with grade 2/4/3 based on SINCLAIR SCALE for disease severity having the ability for regular visits Not receiving previous treatment in the last three months age between 18-55 not having contraindication for minoxidil 5% and botulinum toxin
Exclusion criteria
Exclusion criteria: Having needle phobia Having alopecia areata and another hair diseases(LPP) Having neuromuscular disease Previous use of corticosteroids or immunosuppressive drugrs in the last 3 months Having localized infection Having internal systemic and skin disease or localized dermatosis. Patients with a history of bleeding diseases or under treatment with anticoagulants Previous family or personal history of keloid Having koebner phenomenon Having symptoms of hyperandrogenism and in need for systemic drugs pregnancy and lactation Another treatments in less than 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hair volume and density in qualitative and quantitative way. Timepoint: 3 and 6 months after starting treatment. Method of measurement: photography - photo finder - dermoscopy -self assessment. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHawraa Taleb
Tehran University of Medical Sciences
Outcome results
None listed