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Effect of Linagliptin and Empagliflozine on diabetes

Evaluation the effect of Linagliptin and Empagliflozin combination on glycosylated hemoglobin and fasting blood sugar control in patients with type 2 diabetes

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20221016056201N1
Enrollment
55
Registered
2023-02-08
Start date
2023-02-09
Completion date
Unknown
Last updated
2023-03-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetes type 2. Type 2 diabetes mellitus

Interventions

Intervention group: type 2 diabetic patients resistant to other oral anti-diabetic treatments (metformin, glybenclamide and acarbose) whose FBS and HbA1C are not within the therapeutic range despite r

Sponsors

Arak University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: patients who have been diagnosed with type 2 diabetes mellitus based on the ADA diagnostic criteria and indicated for medical therapy patients who have not reached to treatment goals despite receiving previous medications

Exclusion criteria

Exclusion criteria: type 1 diabetes pregnancy diabetic ketoacidosis (present and previous) pancreatitis (present and previous) diabetic foot ulcer (present and previous) GFR less than 30 BMI less than 18.5 severe adverse drug reactions lack of consent to participate in the study untreated urinary tract infection

Design outcomes

Primary

MeasureTime frame
Fasting blood sugar. Timepoint: beginning of the study, 3 months later. Method of measurement: blood sample.

Secondary

MeasureTime frame
Glycosylated hemoglobin. Timepoint: beginning of the study, 3 months later. Method of measurement: blood sample.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Davari

Arak University of Medical Sciences

buccynator@gmail.com+98 86 3836 2221

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026