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evaluation the effect of Alnavar drug on patients with low ovarian reserve in ivf cycle

Comparision of corifollitropin alfa versus recombinant FSH in poor ovarian responders

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20221016056198N1
Enrollment
90
Registered
2022-11-22
Start date
2022-10-19
Completion date
Unknown
Last updated
2023-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

diminished ovarian reserve in IVF cycle. Female infertility of other origin

Interventions

Intervention 1: Intervention group that recieved corifolitropin alfa(Elonva),100 microgeram,start at 2th day of mense,Behestan daroo factory. Intervention 2: Control group that recieved recombinant FS

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Patients with hystory of previous cycle ; that who fulfilled at least two of the following criteria were admitted: Antral follicle count (AFC) <?5;Antimullerian hormone (AMH)?<?1,1?ng/ml;Less than three oocytes obtained in the previous cycle;

Exclusion criteria

Exclusion criteria: uterine abnormalities, recent or current history of any current untreated endocrine abnormality, unilateral or bilateral hydrosalpinx contraindications for the use of gonadotropins

Design outcomes

Primary

MeasureTime frame
The rate of continuous pregnancy is defined despite the intrauterine gestational sac with a fetal pole that shows cardiac activity during the 9th to 10th week of pregnancy. Timepoint: 9-10week after embryo transfer. Method of measurement: trans vaginal sonography.;Clinical pregnancy rate, which is defined as the presence of an intrauterine gestational sac in the 7th week of pregnancy. Timepoint: 7week after embryo transfer. Method of measurement: trans vaginal sonography.

Secondary

MeasureTime frame
Implantation rate per number of transferred embryos. Timepoint: 3-5 weeks after embryo transfer. Method of measurement: trans vaginal sonography.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNazanin Hajizadeh

Shahid Beheshti University of Medical Sciences

hajizadeh.nazanin94@yahoo.com+98 21 2243 2600

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 5, 2026