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The effect of circadian rhythms modulation for gait initiation in people with Parkinson’s disease

The effect of circadian rhythms modulation on anticipatory postural adjustments for gait initiation in people with Parkinson’s disease

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20221014056170N1
Enrollment
16
Registered
2023-01-09
Start date
2023-01-21
Completion date
Unknown
Last updated
2023-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Parkinson disease. Parkinson's disease

Interventions

Intervention 1: Intervention group: They will wear glasses for two weeks. At the time of receiving the intervention (TEBL), the participants will be asked to wear glasses that shine active bright ligh

Sponsors

Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 75 Years

Inclusion criteria

Inclusion criteria: Age between 40 and 75 years. Idiopathic Parkinson's disease diagnosed by a neurologist. Being in stages 2 and 3 of the disease based on the Hoehn and Yahr scale. The ability to walk independently without the need for mobility aids (such as canes and walkers) for 30 minutes.

Exclusion criteria

Exclusion criteria: Presence of accompanying neurological disorders or history of other neurological disorders or major psychiatric illness. The presence of cognitive disorders affecting the study. Drug and alcohol addiction. The presence of vision and hearing problems, which affect the patient's ability to perform the test correctly. The presence of sensory problems in the legs or musculoskeletal disorders in the lower limbs. Suffering from chronic back pain and the presence of a prosthesis in the lower limb that limits the range of movements. Having severe tremors, a score greater than 2 on any of the items 3.15a to 3.17e on the clinical test (MDS-UPDRS). History of episodes of freezing of gait or dyskinesia History of implant surgery (Deep brain stimulation or DBS)

Design outcomes

Primary

MeasureTime frame
Circadian rhythms function. Timepoint: Measurements will be taken before using the glasses and 14 days after using the glasses. Method of measurement: Examining the daily sleep pattern.;Anticipatory postural adjustment. Timepoint: Measurements will be taken before using the glasses and 14 days after using the glasses. Method of measurement: Gait analysis and Electromyography indicators.;Gait initiation. Timepoint: Measurements will be taken before using the glasses and 14 days after using the glasses. Method of measurement: Gait analysis and Electromyography indicators.;Severity of Parkinson's disease. Timepoint: Measurements will be taken before using the glasses and 14 days after using the glasses. Method of measurement: Unified Parkinson’s Disease Rating Scale or UPDRS.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactLaila Alibiglou

Iran University of Medical Sciences

laila.alibiglou@gmail.com+98 21 8612 6135

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026