Condition 1: Scars. Condition 2: Burn of head, face, and neck sequela. Condition 3: Burn of trunk sequela. Condition 4: Burn of limbs sequela. Condition 5: Burn of Lower Limb sequela. Condition 6: hypertrophic scar. Scar conditions and fibrosis of skin Burn of unspecified degree of head, face, and neck, unspecified site, sequela Burn of unspecified degree of trunk, unspecified site, sequela Burn of unspecified degree of shoulder and upper limb, except wrist and hand, unspecified site, sequel
Conditions
Interventions
Intervention 1: First, the subcision and release of adhesions in the subdermal area of the specified location for fat injection are performed with a standard blunt cannula with a diameter of 1.5 mm. A
Sponsors
Iran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Burn-induced scars anywhere on the trunk or limbs or face or neck The minimal interval between burn injury and intervention(fat grafting) should not be less than one year(Mature Scars)
Exclusion criteria
Exclusion criteria: Any significant systemic disease or morbidity ( e.g. Cardiac disease, Endocrine disease, Respiratory Disease etc) Any patient with an American Society of Anesthesiologist Physical Status Classification System score>II indicating increased anesthesia risk Low Body Mass Index (BMI) (Less than 19kg/m²) Known Systemic Immune Disorder (Acquired or inherited immune deficiency)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall Scar Score (Observer). Timepoint: Before intervention and three months after intervention. Method of measurement: Patient and Observer Scar Assessment Scale (POSAS) Questionnaire.;Overall Scar Score (Patient). Timepoint: Before intervention and three months after intervention. Method of measurement: Patient and Observer Scar Assessment Scale (POSAS) Questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Scar Vascularity. Timepoint: Before interventions and three months after intervention. Method of measurement: Patient and Observer Scar Assessment Scale (POSAS) Questionnaire.;Scar Pigmentation (Observer Score). Timepoint: Before interventions and three months after intervention. Method of measurement: Patient and Observer Scar Assessment Scale (POSAS) Questionnaire.;Scar Thickness (Observer Score). Timepoint: Before interventions and three months after intervention. Method of measurement: Patient and Observer Scar Assessment Scale (POSAS) Questionnaire.;Scar Relief (Observer Score). Timepoint: Before interventions and three months after intervention. Method of measurement: Patient and Observer Scar Assessment Scale (POSAS) Questionnaire.;Scar Pliability (Observer Score). Timepoint: Before interventions and three months after intervention. Method of measurement: Patient and Observer Scar Assessment Scale (POSAS) Questionnaire.;Scar Surface Area. Timepoint: Before interventions and three months after intervention. Method of measurement: Patient and Observer Scar Assessment Scale (POSAS) Questionnaire.;Scar Pain. Timepoint: Before interventions and three months after intervention. Method of measurement: Patient and Observer Scar Assessment Scale (POSAS) Questionnaire.;Scar Itching. Timepoint: Before interventions and three months after intervention. Method of measurement: Patient and Observer Scar Assessment Scale (POSAS) Questionnaire.;Scar Color Difference (Patient Score). Timepoint: Before interventions and three months after intervention. Method of measurement: Patient and Observer Scar Assessment Scale (POSAS) Questionnaire.;Scar Stiffness (Patient Score). Timepoint: Before interventions and three months after intervention. Method of measurement: Patient and Observer Scar Assessment Scale (POSAS) Questionnaire.;Scar Thickness (Patient Score). Timepoint: Before interventions and three months after intervention. Method of measurement: Patient and Observer Scar Asse | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSeyyed-ehsan Mousavi-lajimi
Iran University of Medical Sciences
Outcome results
None listed