The effect of albumin administration on mortality rate, lung involvement rate and blood oxygen in patients with covid-19 hospitalized in the intensive care unit

Comparison of the effect of albumin administration on attenuation, lung involvement and blood oxygenation of patients with Covid-19 admitted to intensive care unit with albumin level less than 3 and 2 g dl ( Clinical Trial )

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20221011056144N1

Enrollment

Registered

2022-12-14

Start date

2022-12-10

Completion date

Unknown

Last updated

2023-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with covid-19. Covid-19, Virus identified

Interventions

Intervention 1: Intervention group: After albumin reaches a level of less than 3 grams per deciliter, 20% albumin in 50 ml vials (company: CSL BEHRING, country of manufacture: Germany) will be adminis

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age 18 years and above PCR test positive Observation of lung involvement in CT scan Hypoxia (arterial oxygen saturation less than 90%) Patients with consent to participate in the study

Exclusion criteria

Exclusion criteria: Hypoxia (arterial oxygen saturation more than 90%)

Design outcomes

Primary

Measure	Time frame
Mortality rate. Timepoint: Seven days after treatment. Method of measurement: Based on the patient's file.;Lung involvement rate. Timepoint: Seven days after treatment. Method of measurement: CT scan findings.;Blood oxygen saturation percentage. Timepoint: Seven days after treatment. Method of measurement: Non-invasive monitoring device.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAfsaneh Zandi MD

Karaj University of Medical Sciences

afsanehzandi24@gmail.com0098 26 344420

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026