Premature Rupture of Membrane. Premature rupture of membranes
Conditions
Interventions
Intervention 1: Mothers with premature rupture of membrane between 34 to 36 weeks of gestational age, in which betamethasone ampoule with a dose of 12 mg (3 ampoules of 4 mg at once) is injected intra
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Mothers with Premature rupture of membranes At 34 to 36 weeks of pregnancy Singleton pregnancy
Exclusion criteria
Exclusion criteria: Symptoms of chorioamnionitis in mother:fever, tachycardia Infants small for gestational age Infants large for gestational age Any indication of emergency termination confirmed by fetal assessment Maternal diabetes Passing more than 48 hours from rupture of membrane
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| RDS Score. Timepoint: after birth of neonate. Method of measurement: Completion of RDS Score with inspection and auscultation.;APGAR Score. Timepoint: 1 and 5 minute after birth. Method of measurement: inspection of neonate.;Need for Surfactant administration. Timepoint: during first 3 day of life. Method of measurement: medical record of neonate.;Maternal chorioamniotitis. Timepoint: since rupture of membrane till 48 hours after delivery, every 6 hours. Method of measurement: existence of clinical signs : fever and tachycardia. | — |
Secondary
| Measure | Time frame |
|---|---|
| Local infection of mother. Timepoint: One week till one month after delivery. Daily during hospitalization and weekly after discharge. Method of measurement: Observation of c section incision and perineum of mother and assessment for infection signs.;Neonatal death. Timepoint: 28 days after birth. Method of measurement: neonatal medical record. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactZahra Naeiji
Shahid Beheshti University of Medical Sciences
Outcome results
None listed