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The effect of intra-uterine injection of autologous lymphocyte and platelet-rich plasma on the pregnancy rate

The comparison of intra-uterine injection of autologous lymphocyte and platelet-rich plasma on the pregnancy rate in women with recurrent implantation failure

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20221010056132N1
Enrollment
96
Registered
2022-10-31
Start date
2022-11-06
Completion date
Unknown
Last updated
2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Recurrent implantation failure. Supervision of pregnancy with history of infertility

Interventions

Intervention 1: Control group: transfer of embryos in this group of patients with recurrent implantation failure after being placed in the cycle of ovarian induction, is done without any intervention.

Sponsors

Iranian academic center for education culture and research
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
No minimum to 40 Years

Inclusion criteria

Inclusion criteria: Experience at least 2 implantation failures in IVF/ICSI Primary infertility Endometrial thickness less than 6 mm at the time of ovulation induction Age less than 40 years Regular menstrual cycles Body mass index<30 Absence of uterine pathology and infection unexplained infertility Infertility with tubal causes

Exclusion criteria

Exclusion criteria: Polycystic ovary syndrome Uterine pathology Referring due to male infertility Presence of hydrosalpinx Presence of endometriosis.

Design outcomes

Primary

MeasureTime frame
Biochemical pregnancy: through a quantitative beta-human chorionic gonadotropin pregnancy test. Timepoint: 2 weeks after embryo transfer. Method of measurement: Quantitative beta-human chorionic gonadotropin pregnancy test.;Clinical pregnancy: pregnancy confirmed by high levels of human chorionic gonadotropin-beta and ultrasound confirmation of pregnancy sac or heartbeat. Timepoint: Three to five weeks after embryo transfer. Method of measurement: Vaginal ultrasound.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactLeila Naserpour

Iranian academic center for education culture and research

leilanasery48@gmail.com+98 25 3285 9856

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026