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Effect of nanocurcumin in heart failure

The effect and safety of nanocurcumin on patients with heart failure reduced EF (HFrEF)

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20221007056110N1
Enrollment
60
Registered
2022-10-25
Start date
2022-10-23
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

heart failure reduced EF. Systolic (congestive) heart failure

Interventions

Intervention 1: Intervention group: 30 patients with HErEF which are admitted with congestion and decompensated symptoms will receive 40 mg nanocurcumin capsule twice a day for 7 days and standard the

Sponsors

Bagheiat-allah University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients with reduced EF heart failure Signing an informed consent form

Exclusion criteria

Exclusion criteria: No history of rheumatologic disease No active infection No acute kidney injury

Design outcomes

Primary

MeasureTime frame
Interleukin 6. Timepoint: At the beginning of the study and after receiving the last dose of nanocurcumin. Method of measurement: Laboratory tests.;NT-proBNP. Timepoint: At the beginning of the study and after receiving the last dose of nanocurcumin. Method of measurement: Laboratory tests.

Secondary

MeasureTime frame
Serum creatinine. Timepoint: At the beginning of the study and after receiving the last dose of nanocurcumin. Method of measurement: laboratory tests.;WBC count. Timepoint: En At the beginning of the study and after receiving the last dose of nanocurcumin. Method of measurement: laboratory tests.;ALT. Timepoint: At the beginning of the study and after receiving the last dose of nanocurcumin. Method of measurement: laboratory tests.;AST. Timepoint: At the beginning of the study and after receiving the last dose of nanocurcumin. Method of measurement: laboratory tests.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactEmadoddin Hosseinjani

Shahid Beheshti University of Medical Sciences

e.hosseinjani@sbmu.ac.ir+98 21 2360 2280

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026