Poly cystic ovarian syndrome. Polycystic ovarian syndrome
Conditions
Interventions
Intervention 1: Astaxanthin group: In this group, patients will receive a 6 mg astaxanthin tablet daily for two months after eating. Intervention 2: Control group: In this group, patients will receive
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: Diagnosis of Poly cystic ovary syndrome based on Rotterdam criteria People are in the age range of 18 to 40 years
Exclusion criteria
Exclusion criteria: Pregnancy Adrenal hyperplasia and androgen secreting tumors Male infertility factors
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Measurment of serum cytokine levels in patients with polycystic ovary syndrome. Timepoint: At the beginning of the study before the start of the intervention and two months after the start of astaxanthin. Method of measurement: ELIZA.;Measuring the expression level of Wnt/ß-catenin signaling pathway genes in patients' granulosa cells. Timepoint: Two months after the start of astaxanthin. Method of measurement: Real time PCR test.;Measuring the level of expression of the phosphorylated and dephosphorylated form of beta-catenin protein. Timepoint: Two months after the start of astaxanthin. Method of measurement: Western blot test. | — |
Secondary
| Measure | Time frame |
|---|---|
| Checking the quality of oocytes. Timepoint: Two months after taking astaxanthin. Method of measurement: Observation with inverted microscope.;Checking the rate of fertilization fertilization. Timepoint: Two months after taking astaxanthin. Method of measurement: Observation with microscope. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactRategar Tayebe
Tehran University of Medical Sciences
Outcome results
None listed